Journal: Addiction Biology
Article Title: Morphine exposure modulates dimensional bias and set formation in anthropoids
doi: 10.1111/adb.13380
Figure Lengend Snippet: Dimensional bias in response time and its interaction with morphine exposure. (A) The mean (±SEM) normalized response time in humans is shown for colour and shape dimensions. Response time was significantly shorter when participants responded in the colour compared with shape dimension. (B) Mean normalized electrodermal activity (EDA) in humans is shown for colour and shape dimensions. EDA was significantly lower when participants responded in the colour compared with shape dimension. (C). Mean normalized response time in monkeys is shown for colour and shape dimensions. In contrast to humans, response time was significantly shorter when monkeys responded in the shape compared with colour dimension. (D) Mean normalized response time is shown for colour and shape dimensions in the pre‐morphine and post‐morphine testing sessions. Exposure to morphine interacted with expression of dimensional bias and exaggerated the response time difference between colour and shape dimensions. (E) The difference between colour and shape dimensions for raw response time (dimensional bias) is shown in the pre‐morphine and post‐morphine testing sessions. Dimensional bias was significantly increased in the post‐morphine testing
Article Snippet: Two surface electrodes were attached to participants' non‐dominant ring and index fingers, which were connected to an electrodermal recording amplifier (ML116 GSR Amp, ADInstruments) sampling at a rate of 75 kHz.
Techniques: Activity Assay, Expressing